Explore the World of Cosmetic Plastic Surgery, Medical Spa, and Skin Care from Indianapolis Plastic Surgeon, Dr Barry Eppley

Archive: clarian west medical center

Understanding Eyelid Surgery
Posted on 23 April 2008 | Category: blepharoplasty, clarian north medical center, clarian west medical center, dr barry eppley, eyelid surgery, indianapolis, plastic surgery

Eyelid surgery, known as blepharoplasty, is one of the most common aging facial surgeries. This is not only because every person has four eyelids (4 surgeries per patient) but because it is often the first plastic surgery procedure (not an office-based procedure such as Botox) one may go through to deal with the effects of aging. Because the eyes are seen by everyone (every human conversation is based on heavy eye contact), we are all too aware of when we appear tired even if we aren’t. The eyes may be the window to the soul but they are also the shades to the eyeball whbich do weather with age.
Aging of the eyelids is a result of three things; 1) The constant muscle movement around the eye causes the skin to wrinkle and create folds (lower eyelid) and hooding (upper eyelid), 2) eyelid skin starts to sag due to gravity, and 3) fat starts to protrude out from under the eye (lower eyelid bags) much like a hernia. All three aging conditions cause the eyelids to look heavy, saggy and swollen creating a very tired appearance. The eyelids can be made to look worse if one’s brow also starts to sag, making the skin on the upper eyelid look even worse.
Surgical correction of these aging eyelid problems is to remove the ‘extra’ skin’, remove or push back the herniated fat (lower eyelid), and sometimes even tighten the corners of the eye. On the upper eyelid, a large amount of skin can be removed leaving a very fine scar along the natural upper eyelid crease. Sometimes fat is removed in the upper eyelid but it is not as big of a problem as it is in the lower eyelid. A surprising large amount of skin can be removed in the upper eyelid without causing any problems with eyelid closure. In the lower eyelid, however, the reverse is true. Managing the herniated fat is a very important part of lower eyelid surgery. Whether the fat that protrudes is removed or, in a newer technique, tucked back up under the eye like a hernia repair, getting rid of excess lower eyelid fat is key to a good result for most patients. Removal of skin in the lower eyelid, however, must be done very carefully and much less can be removed than one would think. If just a little too much is removed, the risk of the lower eyelid pulling down after surgery is a real possibility. For this reason, particularly in the older patient, the lower eyelid which is often loose anyway is tightened like a clothesline at the side of the eyelid where it attaches to the bone.
When all four eyelids are done at the same time (which is most common), the overall effect can be quite dramatic. And since everyone looks at our eyes in conversation, the more youthful and refreshed appearance is appreciated by all even though most do not know it is from plastic surgery.
Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

The Three Layers of a Tummy Tuck
Posted on 08 April 2008 | Category: abdominoplasty, clarian north medical center, clarian west medical center, dr barry eppley, indianapolis, plastic surgery, tummy tuck

I often call a tummy tuck, medically known as an abdominoplasty, as the ‘facelift’ of the body. It is a dramatically effective procedure that makes a change in the mid-section of the body that no amount of exercise or weight loss can ever do. While it is not a simple and quick recovery, the long-term benefits are enormous for most patients. The analogy of a tummy tuck to a facelift is a good one, because the surgery is all about layers. Removing and moving different layers of the abdominal wall to get the desired effect.
Whatever you don’t like about your stomach and waistline area, what you are seeing is a function of the three layers; skin, fat, and muscle. Each patient’s problem’s is composed of different contributions (excess or looseness) of these three layers. Knowing the contributions of each goes a long way in picking the right tummy/waistline solution.
If ones stomach area or waistline is full but the overlying skin is not loose, for example, then this problem is better treated by liposuction and you probably don’t need a tummy tuck. If, however, the stomach skin is loose, has stretch marks, sticks out, if you have had children, then some variation of a tummy tuck is probably in order. A tummy tuck deals with all three layers of the problem; removing loose skin, excess fat (even in areas where skin is not removed), and tightens the muscle. This three-layer approach produces the best result as all problem layers are adjusted.
Tummy tucks come essentially in two varieties; a mini- or limited tummy tuck and a maxi- or full tummy tuck. The fundamental difference between the two is in the amount of skin removed. If the cut-out of skin and fat is done below the belly button, this falls into the mini-tummy tuck variety. In this more limited operation, a new belly button does not have to be created, at the price of cutting out less skin. In the full tummy tuck, the cut-out of skin and fat goes above the belly button. A new belly button hole is needed to bring out the original stalk of the belly button. In either case and for most patients, liposuction is done around the waistline and into the back removing fat from areas that the cut-out does not reach. This is an extremely valuable companion procedure as you need to think of this operation as a 270 degree result, not just a 180 degree (or frontal only) effect.
Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.ologyspa.com/
http://www.eppleytummytuck.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

The Layers and Vectors of a Facelift
Posted on 30 March 2008 | Category: clarian north medical center, clarian west medical center, discover plastic surgery, dr barry eppley, facelift, indianapolis, jowl lift, necklift

A facelift is one of the most recognized procedures in aesthetic plastic surgery…..but also one of the most misunderstood. The general public’s perception of a facelift….based on TV shows and the internet…is someone after such surgery being bruised from their eyes to their neck and their face wrapped up in a big dressing…like they had been involved in a major accident. And that it will take weeks to even look good enough to go out in public. In reality, this perception is flawed at best and even grossly inaccurate at worst.
The name of the operation, facelift, is misleading. It does not really describe what the surgery actually does or what the objectives of the procedure are. More accurately, a facelift should be called a neck-jowl lift, for this is what it actually helps. It is a great procedure for tightening the neck, getting rid of the that neck waddle, and lifting those sagging jowls. The medical name for a facelift, rhytidectomy (old plastic surgery meaning cutting out wrinkles), should be described as a cervicoplasty. (reshaping of the neck) However, the name facelift persists and always will as it is embedded in our plastic surgery nomenclature.
Therefore, when you realize that only the neck and jowl are affected by the procedure, many of its misconceptions fade away. In isolation as a stand-alone procedure (which half of my ‘facelift’ patients only have), a facelift causes no bruising or swelling from the nose up. While many facelift patients get their eyes, forehead, nose and other facial procedures done at the same time, this is not a requirement and is only done if one wants the ‘total face’ rejuvenated. I find that after an isolated facelift, one can look pretty good in about a week and can easily be out in public in a few days with a little make-up in the neck area.
Remember, the eyes are not swollen at all!
One of the great misconceptions about a facelift is what is actually done in the operation. A facelift operation is all about tissue layers and vectors of lifting. The lifting off of the skin from the underlying tissues over the side of the face (to the cheek area) and across the neck through incisions placed in and around the ears is obvious in any diagram of a facelift operation. And movement of loose skin pulled back and over the ears at about a 45 degree angle to the face probably accounts for about 80% - 90% of the result created by a facelift. And often this is the only tissue moved in a facelift. This is the safest and easiest approach with the least likelihood of complications. Deeper layers have also been raised up and moved in more recent versions of facelift surgery. These deep layer that can be moved independent of the skin, is a special layer of tissue over the muscle. This tissue, known as SMAS, is raised and sutured up in a more vertical direction compared to the direction of the skin pull, closer to 60 degrees usually. The public erroneously believes that it is muscle that is moved which is not possible. The SMAS sits on top of the muscle. There is considerable debate as to whether the ‘deeper’ versions of the facelift produce better long-term results than skin movement only.
The neck-jowl lift, known historically as a facelift, can lift two different layers of sagging facial tissues in two slightly different up and backward directions.
Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.eppleyfacelift.com
http://www.ologymd.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

The Anatomy of a Rhinoplasty
Posted on 15 March 2008 | Category: clarian north medical center, clarian west medical center, discover plastic surgery, dr barry eppley, indianapolis, nose surgery, rhinoplasty

Rhinoplasty (nose surgery) is one of the top ten requested cosmetic procedures for both men and women in plastic surgery. The prominence of the nose and its significance to the appearance of the face makes the need for any rhinoplasty surgery to be very precise. Good results in rhinoplasty are dependent upon an understanding of the complex framework of bone and cartilage that make up the nose. Rhinoplasty surgery changes the shape of this framework which is revealed through the overlying skin.

Think of your nose as a house. The shingles are the overlying skin, the framework and timbers are the cartilage and bone, and the drywall the nasal lining. The support that lies underneath the highest roof angle is the septum. (cartilage) What makes anyone’s nose look the way it does, like a house, is a reflection of how the framework is structured and the roof (skin) that drapes over this framework. As plastic surgeons we think of the nose as 4 areas, the upper 1/3 which is bone, the middle 1/3 known as the middle vault which is all cartilage which is straight, and the lower 1/3 or the tip of the nose which is a combination of scroll-shaped cartilages that come together over the septum and is what gives everyone their unique tip shape. (which is the most different between any two people) The fourth area is the skin, which dependent upon its thickness, can show the underlying framework well if it is thin but can hide much of it if it is thick.

When we alter the nose we are changing the way the framework (bone and cartilage) is joined together and is shaped. This could be taking down the height of the roof in one area (that bump on your upper nose), reshaping the tip of the nose (by changing the shape of the scrolled cartilages, breaking the bone along the bridge to narrow the nose (collapsing the walls), or in some cases adding to the roof line with implants or cartilage to raise the height of the roof line.

Due to the complexity of how all of these framework structures come together, most rhinoplasties today are done ‘open’. While this used to be a controversial area (what was known as the most contested 6 millimeters of skin on the body), it is now accepted to produce the best results in most nose surgeries. All that this means is the skin is lifted off of the tip of the nose so all the framework structures can be seen. To no surprise, you can shape better what you can see better. This only leaves a nearly imperceptible scar at the middle of the skin between your nostrils. (known as the columella) This is a very small price to pay for a better rhinoplasty result!
Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.eppleyrhinoplasty.com
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

The Mechanics of Liposuction
Posted on 09 March 2008 | Category: clarian north medical center, clarian west medical center, discover plastic surgery, dr barry eppley, fat removal, indianapolis, liposuction

Liposuction, after 25 years since its introduction in the United States in 1981, remains one of the most popular plastic surgeries for both men and women. How it works seems simple enough…’stick a tube and suck it out’ to paraphrase what many patients say. And while it is conceptually simple mechanical process, there is more to it than meets the eye.

At its most basic level, liposuction is a simple two-stage process for removing fat. A hollow tube (cannula) is put under the skin, the tube is moved back and forth until the fat is dislodged, and the attached vacuum source draws the fat back through the cannula into the tubing and finally into the plastic bottle.

Despite this apparent simplicity, there is more science to it than that. There are three interesting components about liposuction, all of which contribute to its safety and effectiveness. These include tumescent fluid infiltration, vacuum pressure, and cannula size and design.

The placing of fluid during the liposuction operation before doing the suctioning is an integral part of the operation. I frequently get asked by patients if I do tumescent liposuction. Patients think that this is a special method of liposuction, when in fact, it is used in every liposuction procedure. Putting large amounts of fluid into the fat areas to be suctioned beforehand is known as tumescent infiltration. This achieves two fundamental things, substantially reduces bleeding (from the fat being broken up by the liposuction tube and it distends the fat compartments which make the tube easier to pass through the fat being suctioned. Without tumescent infiltration, liposuction would quite bloody, give patients more pain, and have them bruised for a month, if not longer.

The amount of suction generated by the liposuction machine, in short, makes liposuction possible. At the accepted amount of suction needed for liposuction (-20 cms of water or -1 atmosphere of pressure), the pulling of fat through the tubing certainly occurs. But it also causes the vaporization of water. If you have ever witnessed an actual liposuction procedure, you may have seen bubbles in the fat or bubbling in the plastic cannister. To some degree, this is actually water boiling….or the pressure in the system falling to the vapor pressure of the water in the fat being removed. It is this vaporization that makes the viscosity (how thick it is) of fat, which is actually a combination of fat, blood, and infiltration fluid, less to improve its ease of flow through the tubing. From a flow standpoint, water that is vaporized ( a gas) flows 100 times faster than liquid water. This is also why liposuction done at higher altitudes, where the water vapor of pressure is less, is somewhat easier to do. (takes less suction from the machine)

The tube (cannula) that is actually used under the skin differs in diameter and the holes at the tip. In days gone by, the cannulas were quite large but left a lot of depressions in the overlying skin after due to removing too much fat too fast and in large pieces. Today, small cannulas are used which removes fat more carefully and in smaller pieces, decreasing the problem of skin irregularities after surgery. The tip of the cannula is rounded so that it travels through the fat easier with less chance of penetrating something you shouldn’t. The holes at the tip are where fat sticks to and then gets sucked into the cannula. The more holes there are at the tip achieves two effects; increases the shearing effect (like a blade) on fat and makes more cross-sectional area through which fat can be suctioned.

Currently, there are newer methods of liposuction or to be accurate, methods of loosening up the fat. These include ultrasonic and laser-assisted. While they sound quite advanced (and they are), there is no convincing evidence at this time that they are actually better than traditional liposuction. Better meaning….you get more fat removed, smoother results, and recover faster with less bruising and pain. They are marketed by the manufactures as such but there is no solid science to prove it. And they still require suction to pull out much of the loosened or liquefied fat.

Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.eppleyliposuction.com
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

Chin Augmentation With An Implant
Posted on 24 February 2008 | Category: chin augmentation, chin implant, clarian north medical center, clarian west medical center, discover plastic surgery, dr barry eppley, indianapolis

How is a Chin Implant done?
Short chins (both in height and in length) are good indications for what we call alloplastic mentoplasty, otherwise known as a chin augmentation using a synthetic implant. Chin implants are by far and away the most common method for enlarging one’s chin. Its principal advantage is that it is simple and quick to do, allows for a rapid recovery, and the result is very predictable with a high patient satisfaction rate.
A wide variety of synthetic materials have been used in the chin but the standard over time continues to be solid silicone. It is well tolerated, flexible, easy to insert and remove, can be easily manufactured in an endless number of configurations and sizes, and is inexpensive. Its flexibility allows even large extended implants to be placed through small incisions. As of this writing, porous polyethylene (Medpor) is the lone alternative and good results can be achieved with its use although it is more expensive, requires greater intraoperative time and effort for fashioning and placement, and is more difficult to remove should that ever be necessary.
The chin implant is almost always put in through a small incision on the underside of the chin in the submental crease. This provides a direct approach for placement of the implant (shortest distance to the bone) and allows liposuction and neck tightening procedures to be done through the same incision. The chin implant is slide into position on the bone after a pocket has been made that will accomodate its size. Once in place, it is either sewn or screwed into place and the tissue closed over it. While a chin implant can also be placed through the mouth (a common approach done by many oral surgeons), placing it this way disrupts the main chin muscle and the risk of having the implant riding too high on the chin bone after surgery unless the implant is secured by screws to the bone.
The chin implants used today are quite different from those used in the past. Today’s chin implants are better by having ‘wings’ that extend out further to make a smoother transition to the bone on the side of the chin out on the jaw. This allows for the creation of increased width to the chin and improved blending into the lateral body of the mandible without irregular transition zones. The size and style of chin implant chosen is done by pre-surgical imaging of the face and chin and looking at how the different sizes change one’s profile.
Chin implants are a very safe procedure that has few complications if done well. Infection after surgery is rare but the implant could be salvaged by antibiotics alone if it occurs in the early postoperative period. Thereafter, implant removal is usually required for resolution. Some temporary lower lip numbness can occur but this resolves quite quickly after surgery.

Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

The Art and Design of a Breast Reduction
Posted on 12 February 2008 | Category: breast reduction, clarian north medical center, clarian west medical center, dr barry eppley, indianapolis, reduction mammoplasty

Breast reduction surgery, also known as reduction mammoplasty, was performed on over 175,000 patients in 2006 (over 20,000 were in men but that is a very different topic that breast reduction in a female and will not be covered here) It is a frequently sought-out procedure by many large-breasted women, young and old, for one very good reason…it is tremendously effective at reducing or eliminating the back, shoulder, and neck pain that comes from carrying such weight around on their chests and upper stomachs. This explains why the scars that result from the surgery, while not always ideal from a plastic surgeon’s viewpoint, seem to be a good trade-off for the vastg majority of patients who undergo the procedure.

Breast reduction is one of the few plastic surgery procedures that can still get consistently covered by medical insurance….if the patient qualifies. Qualifications include large breasts given one’s height and weight, evidence of problems with the breasts such as shoulder grooves and skin rashes under the breasts, and evidence that conservative treatment methods such as physical therapy, chiropractic treatments, or pain medications have not worked.

So if you qualify, how does a breast reduction operation work? A breast reduction is done by a precise cut-out pattern that is based on one single concept…….remove breast tissue, tighten skin, and…..keep the nipple alive! If it weren’t for the nipple, a breast reductiuon operation could be done twice as fast and could be reduced to any size, no matter how small. But that circle of pinkish-colored tissue changes how the whole procedure must be done.

The nipple is keep alive by making sure that enough blood supply gets to it from below both during and after surgery.. This means the nipple is never removed (there is a variation of a breast reduction procedure known as breast reduction with free nipple grafting…but that is not what we are talking about…and is rarely sued today) This means that a central core or central pedicle of breast tissue undeneath the nipple must be maintained for the blood supply to get through. So, as the breast tissue is being removed, the central pedicle gets smaller and smaller but canc only be reduced so much. How much can never be precisely known during surgery so it is an art to know how far to push the limited of breast tissue removal from the central pedicle. My rule of thumb is….I would rather leave a little too much and have a live nipple after surgery….than remove too much and have a smaller breast with with a dead nipple. While we as plastic surgeons do well at reconstructing nipples, a reconstructed nipple is never as good as your original one! Therefore, I tell patients I will not likely go less than 2 cup sizes smaller than where we start for safety’s sake of the nipple. This often is disconcerting to hear for some patients but the improvement that one gets ina breast reduction, in my opinion, is as much due to the skin tightening and lifting the breast back up on the chest wall as it is due to the actual amount of breast tissue removed. (All breast reductions…..are a breast lift too!)

The skin cut-out pattern is the precise design part of the operation. The skin cut-out is based on a simple principle that most grade-school children know……how to make a cone out of a piece of paper! By simply cutting a wedge out of paper and bringing the edges of the paper together….you have a cone! While this conceptual image is not precisely accurate (it is more like a keyhole rather than a simple wedge), you get the picture.

So, breast reduction surgery is……locate the new position of the nipple and mark the skin cut-out pattern (prior to surgery), make the skin cut-out, keep the nipple attached to the breast tissue, remove breast tissue from all sides getting closer to the nipple, and bring the keyhole together. Finally, pick your new spot for the nipple on the cone and bring it through.

Doesn’t sound simple…and it isn’t. The breast reduction operation is a mixture of precise design, art of shaping, and a lot of sewing. And to make matters more difficult…..there are two breasts and you have to match them. It is a lot of work, but very rewarding as those women who undergo it have almost instantaneous relief of much of their pain…and get to go out and finally buy new bras!

Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

The Geometry of Scar Revision in Plastic Surgery
Posted on 27 January 2008 | Category: clarian north medical center, clarian west medical center, dr barry eppley, geometric scar revision, indianapolis, scar revision, scar treatment

Concern about scars, those one already has or those that might occur from an upcoming surgery, is a frequent patient concern. As a plastic surgeon, I see patients weekly that have existing scars from injury or surgery and would like them improved. While scars come in many varieties (see my scar website, http://www.scarscription.com/) and can be treated by numerous methods, a common treatment method is excisional scar revision. Simply put, the actual cutting out of the bad tissue (scar) and putting it together with fresh unscarred skin. While this creates a ‘new’ scar, the goal is that the new scar is better looking than the old one. The fundamental concept is…..no scar can be completely erased (we are physicians, not magicians) but can be made less noticeable.

Scar excision (revision) is appropriate for scars that are wide, raised, depressed, or are a relatively straight line that crosses the relaxed skin tension lines (RSTL) of the face. (RSTLs are the natural cleavage lines of one’s skin that become quite evident when we get old……as wrinkles and folds….scars that lie parallel to the RSTLs will stay narrower and are less noticeable than those that cross it at angles or run perpendicular to them) No amount of time or any other form of scar treatment will make a scar narrower or make its edges flush with the surrounding skin. When a scar is cut out, it can be put back together in numerous geometric ways….depending upon what scar configuration will look better.

If putting the scar back together allows it to lie in a straight line parallelling a RSTL (for example, a horizontal orientation in the forehead or part of a circular pattern around an arm or leg), then a simple straight line closure would be most favorable. If, however, closing the scar makes a line that runs at angles to the RSTL…then a more geometric scar closure pattern may be used.

Geometric scar revision is based on a simple visual concept…..the eye has a harder time following an irregular line than a straight one. If the cutout of the scar and the way it is put back together creates an irregular pattern, then the scar may ultimately be less noticeable. These geometic scar patterns can be done as running Ws (like the pattern created by pinking shears), intermittent Ms, or a variety of other configurations. This type of scar revision is known as a broken-line closure or pattern. The most well-known geometric scar revision is the Z-plasty. Creating a Z along the line of a scar is the ultimate use of geometry. Z-plasties are most commonly used in scars that cross a moving surface (and have created a tight band or scar contracture) such as a joint or when the scar lies directly perpendicular a RSTL on the face. Skin flaps are cut around the skin crease or RSTL and the limbs of the scar flaps interposed. (criss-crossed) A Z scar is subsequently created but, equally important, the scar is actually lengthened across this area. Mathematically, the angle of the skin flaps that are cut determines how much scar length is actually gained. This technique is particularly valuable in the release of scar bands as reorientation and extra length is usally needed so that they do not recur after scar revision.

Geometric and broken-pattern scar revisions are an essential technique for improving many types of scars. These scar revision techniques require a good dose of time after surgery to see their benefits.

Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.scarscription.com/
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

Hyaluron Injectable Soft Tissue Fillers for Facial Lines and Wrinkles
Posted on 08 January 2008 | Category: clarian north medical center, clarian west medical center, dr barry eppley, hyaluron, hyaluronic acid, indianapolis, injectable soft tissue fillers, juvaderm, restylane

The Science of Hyaluron Injectable Fillers in Indianapolis by Dr. Barry Eppley

The use of injectable materials for filling or plumping up facial lines and wrinkles dates back to 1981 in the U.S. when collagen injections became available. From 1981 to 2003, for over twenty years, injectable collagen was the only available facial filler. While the injection process was easy, the popularity of collagen injections was limited as its effects were very short-lived usually lasting around 6 weeks or so. Because the collagen material was bovine-derived (from cows), a skin test was required prior to injection and a small percent of patients had allergic reactions, thus not being capable of treatment. Since 2003, a new synthetic material has become commercially available and collagen is now ‘a material of historic interest’ primarily. This new material is hyaluron or hyaluronic acid.
Hyaluron (HA) is produced today by fermentation in cultures of equine streptococci. The fermented material is then stabilized via epoxidic cross-links of the glycosaminoglycan chains. As a result of this processing method, the HA material does not cause immunologic sensitization and virtually no risk of allergic reactions. Hyaluronan is a polysaccharide that is an essential component of the extracellular matrices in which all human tissues differentiate. In certain tissues, such as the vitreous cavity of the eye and synovial joint fluid, it is the major constituent. Unlike collagen, it is identical across all animal species and microbes. The largest amount of hyaluronan resides in skin, where it is present in both dermis and epidermis. Hyaluronan’s high capacity for holding water and high viscoelasticity give it some unique properties that are useful in various medical and pharmaceutical applications. Because it retains moisture, hyaluronan is used in some cosmetics to keep skin young and fresh-looking. As we age, the water-holding capacity of our skin decreases as hyaluronan depolymerizes. Therefore, the retention or insertion of hyaluronan into the skin is theoretically helpful in wrinkle reduction.
HA can be rather rapidly degraded and is ultimately metabolized in the liver. Modern processing methods have produced more stable forms of HA that have much longer in vivo retention times. As degradation occurs over time, water is attracted to the material at the site of implantation. As the HA concentration decreases, more water bonds to it thus helping with cosmetic persistence. This feature is what probably accounts for its longer volume retention effects than bovine collagen. (isovolemic degradation)
A variety of differing grades of transparent gels are available, based on the same type gel from highly concentrated (20mg/ml)stabilized HA, which varies in particle size and subsequent indication. Restylane has a particulate size of 100,000 gel particles/ml, flows through a 27 gauge needle, and is indicated for mid-dermal applications such as deeper wrinkle reduction, as well as lip augmentation, nasolabial folds, and glabellar creases. Restylane has even been successfully used in the treatment of tear trough deformities.14 Restylane Fine Lines has the highest concentration at 200,000 gel particles/ml, can be injected through a 30 gauge needle, and is indicated for thin superficial wrinkles. The lowest concentration gel is Perlane at 8,000 gel particles/ml which is injected through a 27 gauge needle and is intended for shaping facial contours, correcting deep folds, and for lip augmentation.15 Restylane was FDA-approved in December 2003, Perlane received its approval in 2007. There are numerous manufacturers of HA injectable fillers which, in addition to Restlane, includes Captique and Juvaderm.
The universal HA composition makes the need for pre-injection skin testing unnecessary as the risk for hypersensitivity reactions is minimal. It is easily injected and flows nicely through small-gauge needles. While not permanent, its persistence is reported to exceed bovine collagen with estimates of between 4 and 6 months post-injection.
Rare side effects, that I have not yet seen, include injection site inflammation at an incidence of 0.02% and local hypersensitivity reactions (swelling, erythema, and induration) at an incidence of 0.02% lasting a mean of 15 days.

As of today in 2008, HA injectable soft tissue fillers are the gold standard by which all
future injectable filler materials will be compared.

Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

Silicone Breast Implants in Breast Augmentation
Posted on 06 January 2008 | Category: breast augmentation, breast implants, breast reconstruction, clarian north medical center, clarian west medical center, dr barry eppley, indianapolis, silicone breast implants

Silicone Gel Breast Implants in Breast Augmentation - Scientific Assessment of their Safety

Despite the release of silicone gel breast implants for widespread commerical use in late 2006 and being one of the most (if not the most) studied medical device in history, some patients do question their safety. Any patient over 30 years of age has some recollection of the publicity surrounding the moratorium of silicone gel breast implants back in the early 1990s.

Understanding the science of silicone goes along way in addressing the safety of silicone gel implants for patients when used for both breast augmentation and in breast reconstruction.

First and foremost, silicon as an element is a naturally occurring material (check the Periodic Table) found in sand, quartz and in many types of rocks. It is one of the most common elements that we as humans come into contact with. (oxygen is the most common) When combined with oxygen, carbon, and hydrogen (all naturally occurring elements) in a manufactured process, the polymer silicone is borne. Secondly, silicone has great diversity as a manufactured product and can be made from a liquid form to a solid. It is part of thousands of manufactured products, many of them topical in form for human use. Many of the products used in the beauty industry contain silicone. More relevantly, the use of silicone in medical products is extensive from intravenous catheters to the coatings of joint replacements. As humans, we all have had sufficient exposure to silicone products that most every human alive will test positive for silicone levels.

While silicon is a element and we all have had lots of exposure to it, what does that mean when it is implanted internally in a high volume in one spot? (or in this case, two spots)

The historic conern about the safety of silicone gel breast implants revolves around their potential association with autoimmune diseases. Does a sufficient quantity of silicone, or a long duration of exposure, make the body think it is an immunogen and induce the possibility of autoimmune disease creation?After over 15 years of exhaustive clinical studies, no definitive link between any autoimmune disease (e.g., arthritis, lupus, scleroderma) has yet to be found. The initial link between silicone breast implants and women seemed obvious but the association has turned out to be coincidental as autoimmune diseases have a natural high predilection for women between the ages of 20 and 50, who also are the main recipients of breast implants. The occurrence of autoimmune diseases in women with breast implants is no higher than in women who do not have breast implants. In short, there is no scientific evidence that a silicone gel breast implant increases the risk of autoimmune disease…..or increases the risk of developing breast cancer.

Lastly, it would be hard to imagine that the FDA would re-introduce silicone gel breast implants, and all of the attendant medical-legal risk and liabilities, unless there was absolutely no current evidence of potential harmful effects. As a precaution, the commerical release of silicone gel breast implants comes with a mandate from the FDA…every implanted patient must be enrolled in the Post-Approval Study where further long-term data will be collected over the next ten years. This obligates every implanting plastic surgeon to enroll their patients in this monitored long-term study. The final statement on the safety of silicone gel breast implants will be written in another decade based on hundreds of thousands of implanted women.

Dr Barry Eppley
http://www.eppleyplasticsurgery.com/
http://www.eppleybreastaugmentation.com
http://www.ologyspa.com/
Clarian North Medical Center, Carmel, Indiana
Clarian West Medical Center, Avon, Indiana
Indianapolis

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