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Many injectable fillers used for cosmetic facial augmentation are composed of the substance known as hyaluranon or hyaluronic acid. While it is synthetically produced, it is a natural substance found throughout the body. Known as a glycosaminoglycan or GAG, it is a complex carbohydrate or sugar that is essential for life. Its recognized molecular structure and its ability to attract water is what it makes an excellent filling substance that causes few tissue reaction problems. Its affinity for water absorption is also why it eventually breaks down and is absorbed naturally.

While there are almost a dozen available injectable fillers commercially available currently, the majority of them are hyaluron based. (e.g., Restylane, Juvederm) They are the safest injectable filling material and the most reversible.

Dr. Barry Eppley

Indianapolis, Indiana

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