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Dr. Barry Eppley

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Posts Tagged ‘juvederm ultra xc’

Product Review – Lip Augmentation with Juvederm Ultra XC

Wednesday, October 7th, 2015


Lip Augmentation Dr Barry Eppley IndianpolisLip augmentation is one of the most common and historic procedures for hyaluronic acid-based injectable fillers. It would surprise many then to find out that despite its popularity and common usage, few of these injectable fillers are actually FDA-approved for use in the lips. There are a variety of reasons for this lack of approval but safety and effectiveness are not among them.

On October 1, 2015 the US FDA has approved Juvederm Ultra XC for injection into the lips and perioral (mouth) area for aesthetic augmentation in adults. Juvederm Ultra XC and Juvederm Ultra Plus XC injectable fillers are already FDA-approved for injection for moderate to severe facial wrinkles and folds around the nose and mouth. (nasolabial folds) Juvederm Ultra XC is a well known modified form of hyaluronic acid with prolonged duration (up to a year) that has lidocaine in it to improve the comfort of the treatment.

juvderm ultra xc injectable filler, dr barry eppley indianapolisIn FDA trials of Juvederm Ultra XC for lip augmentation, almost 80% of patients had visible improvement in lip fullness three months after injection. A near similar percent, (78%) stated that they had persistent improvement in lip size one year after injection. The most common adverse effects for Juvederm Ultra XC injectable filler are the same as other hyaluronic acid gels such as temporary swelling, redness and lumps and bumps.

What is unique about Juvederm Ultra XC injectable filler is that it offers long-term retention of lip augmentation results. Many hyaluronic acid-based injectable fillers are used for lip augmentation but their results often last six months or less.

Dr. Barry Eppley

Indianapolis, Indiana

Product Review: Juvederm Ultra and Juvederm Ultra XC

Friday, April 16th, 2010

The use of injectable fillers for fold and wrinkle reduction and lip augmentation rivals that of Botox and Dysport for in-office facial rejuvenation treatments. One advantage of fillers over muscle relaxers is their immediate results that will stay stable as long as the filler material lasts.

At this time, there are over a dozen different types of injectable fillers that are commercially available. This is very confusing to patients since they all have different names, have slightly different to radically different chemical compositions, and the duration of their effects can range from as short as six weeks to over one year.

Despite these apparent vast differences between the numerous injectable fillers, they really are more similar than different. All are FDA-approved and have the same clinical indications. When you distill it down to what matters most, the important issues to patients is two-fold…how long do they last and what do they cost? In other words, which ones provide the best value?

As a general rule, there is some correlation between duration of action and cost. The shorter-lasting injectable fillers are the cheapest and the longer-lasting ones are the most expensive. While there can be wide variability in what a physician or office charges across the country, their still remains a relationship between cost and volume retention as that issue is also reflected on the front end. (what the doctor pays to buy it from the manufacturer)

That being said, I currently find in my Indianapolis plastic surgery practice that Juvederm provides the best value for patients and is highly versatile. (can be used for all facial applications with negligible risk of complications) The newest release from the manufacturer, Juvederm Ultra XC with local anesthetic, just enhances that value. It should be clear in making this statement that I have no relationship with the manufacturer, am not compensated by them or looking to be, and quite frankly have no particular affinity for them or any sales representative that services my practice.

The question is…why do I like Juvederm over the many other injectable fillers products? Being composed of hyaluronic acid (a sugar molecule) and cross-linked in such a way to help resist early degradation, it is incredibly safe and will last close to a year. The manufacturer may state that it lasts a year after injection, but I have found that to not be as accurate as their marketing. It is closer to 9 months most of the time. The time of 9 to 12 months is an interesting window of product duration. For those injectable fillers that last longer than one year, there is an inevitable increase in complications (nodules, inflammatory reactions) which for a cosmetic facial use is not very desireable. If the filler lasts much under 6 months, patients are not happy that they must return to have their face injected again. ( no matter how you cut it that can rank right up there with going to the dentist)

The addition of a numbing agent to the product, Juvederm Ultra XC, is definitely an addition that does help with some decrease in injection discomfort. For parts of the face other than the lips, that helps the experience greatly. For the lips, however, I still perform dental blocks since the numbing from the product will not start to happen until after the needle has penetrated the lip.

From a cost perspective in my practice, the cost of Juvederm may be 1/3 more than Restylane, for example. But at more than two times duration of action, it ic clearly the much better value. 

Dr. Barry Eppley

Indianapolis, Indiana

Dr. Barry EppleyDr. Barry Eppley

Dr. Barry Eppley is an extensively trained plastic and cosmetic surgeon with more than 20 years of surgical experience. He is both a licensed physician and dentist as well as double board-certified in both Plastic and Reconstructive Surgery and Oral and Maxillofacial Surgery. This training allows him to perform the most complex surgical procedures from cosmetic changes to the face and body to craniofacial surgery. Dr. Eppley has made extensive contributions to plastic surgery starting with the development of several advanced surgical techniques. He is a revered author, lecturer and educator in the field of plastic and cosmetic surgery.

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